Lindsay B. Stewart

The translatome of quiescent Plasmodium falciparum gametocytes reveals parasite pyridoxal 5'-phosphate (PLP) biosynthesis is essential for efficient mosquito stage development

Large deletion variants in a Plasmodium falciparum ookinete protein gene and associations with different endemic populations and mosquito vectors

The paper identifies large deletion variants in the PIMMS43 gene of Plasmodium falciparum and shows their geographic frequency variation and potential vector-specific selection.

Competitive multiplication rate variation of Plasmodium falciparum isolates is determined by differences in intrinsic potential

The paper investigates whether variation in multiplication rates of Plasmodium falciparum isolates under competitive conditions is determined by their intrinsic potential, finding a strong correlation with exponential growth rates.

Plasmodium falciparum invasion ligand gene transcript profiles in different populations

The paper compares transcript levels of invasion ligand genes in Malaysian and Gambian Plasmodium falciparum isolates, finding regional differences in eba175, eba181, and Rh2b expression.

Intrinsic multiplication rate variation of Plasmodium falciparum in clinical isolates prior to elimination in Malaysia

The paper examines intrinsic multiplication rates of Plasmodium falciparum in Malaysian clinical isolates, finding no significant difference compared to African isolates, suggesting no adaptation to low transmission settings.

Higher multiplication rates of Plasmodium falciparum in isolates from hospital cases compared with community infections

This study compares Plasmodium falciparum multiplication rates between hospital and community infections, finding higher rates in hospital isolates and a positive correlation with parasitaemia.

Integrated pathogen load and dual transcriptome analysis of systemic host-pathogen interactions in severe malaria

This study uses dual transcriptome analysis to identify host and parasite gene expression associated with severe malaria in Gambian children, showing parasite load explains most human gene expression differences but only a third of parasite gene differences.