Author

Christopher Lemoine

University of ConnecticutORCID 0000-0002-0371-491XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1

Frequent Co-Authors

Gabriela S. Aquino· 2 shared Kyle D. DrakeiD· 2 shared Rahul KanadiaiD· 2 shared Anna M. VaethiD· 1 shared Anouk M. OlthofiD· 1 shared Katery C. Hyatt· 1 shared Marybeth BaumgartneriD· 1 shared Nhut Nguyen· 1 shared

Activity by Year

2018-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersDevelopmental Biology

Gabriela S. Aquino

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2 papers

Recent·Most cited

Developmental BiologybioRxivPreprintMar 16, 2020

Minor spliceosome disruption causes limb growth defects without altering patterning

Kyle D. Drake, Christopher Lemoine, Gabriela S. Aquino…·Rahul Kanadia

This study shows that disrupting the minor spliceosome, specifically by losing U11 snRNA, causes stunted limb growth without affecting limb patterning, due to increased minor intron retention and cell cycle delays.

5 citations

mouseexperimental assay

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Developmental BiologyDevelopmentPeer-reviewedAug 9, 2018

Minor spliceosome inactivation in the developing mouse cortex causes self-amplifying radial glial cell death and microcephaly.

Marybeth Baumgartner, Anouk M. Olthof, Gabriela S. Aquino…·Rahul Kanadia

The paper investigates the role of the minor spliceosome in cortical development by ablating Rnu11 in mice, revealing microcephaly due to radial glial cell death.

63 citations

mousebulk RNA-seq

𝕏 PostBluesky