Author

Gabriela S. Aquino

University of Connecticut

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Developmental Biology· 3

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Approach:experimental assay· 1

Frequent Co-Authors

Kyle D. DrakeiD· 3 shared Rahul KanadiaiD· 3 shared Christopher LemoineiD· 2 shared Marybeth BaumgartneriD· 2 shared Alisa K. WhiteiD· 1 shared Anna M. VaethiD· 1 shared Anouk M. OlthofiD· 1 shared Katery C. Hyatt· 1 shared

Activity by Year

2018-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersDevelopmental Biology

Kyle D. DrakeORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Developmental BiologyDevelopmentPeer-reviewedSep 24, 2021

Trp53 ablation fails to prevent microcephaly in mouse pallium with impaired minor intron splicing

Alisa K. White, Marybeth Baumgartner, Madisen F. Lee…·Rahul Kanadia

This study shows that Trp53 ablation does not prevent microcephaly in Rnu11 cKO mice, but dKO mice show transcriptomic shifts and more severe cell cycle defects.

11 citations

mousebulk RNA-seq

𝕏 PostBluesky

Developmental BiologybioRxivPreprintMar 16, 2020

Minor spliceosome disruption causes limb growth defects without altering patterning

Kyle D. Drake, Christopher Lemoine, Gabriela S. Aquino…·Rahul Kanadia

This study shows that disrupting the minor spliceosome, specifically by losing U11 snRNA, causes stunted limb growth without affecting limb patterning, due to increased minor intron retention and cell cycle delays.

5 citations

mouseexperimental assay

𝕏 PostBluesky

Developmental BiologyDevelopmentPeer-reviewedAug 9, 2018

Minor spliceosome inactivation in the developing mouse cortex causes self-amplifying radial glial cell death and microcephaly.

Marybeth Baumgartner, Anouk M. Olthof, Gabriela S. Aquino…·Rahul Kanadia

The paper investigates the role of the minor spliceosome in cortical development by ablating Rnu11 in mice, revealing microcephaly due to radial glial cell death.

63 citations

mousebulk RNA-seq

𝕏 PostBluesky