Author

Claire H. Woodward

Children's Hospital of PhiladelphiaORCID 0000-0002-0373-6318Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Organism:human· 1 Approach:mechanistic / dynamical model· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1

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Ananya K. MajumdariD· 1 shared Charina S. FabilaneiD· 1 shared Daniel H. HwangiD· 1 shared Ella C. Teeley· 1 shared Gregory R. BowmaniD· 1 shared Jamie B. SpangleriD· 1 shared Michael C. YoungiD· 1 shared Nikolaos G. SgourakisiD· 1 shared

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2024-2024 · peak 1/yr

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1 shared paperBiochemistry

Ananya K. MajumdarORCID

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1 paper

Recent·Most cited

BiochemistryJournal of Molecular BiologyPeer-reviewedJan 1, 2024

Regulating IL-2 immune signaling function via a core allosteric structural network

Claire H. Woodward, Shahlo O. Solieva, Daniel H. Hwang…·Nikolaos G. Sgourakis

This paper investigates how dynamic structural networks in IL-2 superkines affect receptor binding and signaling, showing that modulating core dynamics can improve immune cell selectivity.

1 citation

humanprotein structure

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