J. Christopher Hennings

Democratizing three-dimensional surface phenotyping: an open structured-light platform reveals and removes the projection bias in biological imaging

The paper introduces an open structured-light platform to measure 3D surface phenotypes, revealing that projection bias significantly underestimates surface area and can confound phenotype comparisons.

Urinary Sodium Wasting and Disrupted Collecting Duct Function in Mice with dRTA-Causing SLC4A1 Mutations

This study shows that mice with SLC4A1 mutations exhibit urinary sodium wasting and disrupted collecting duct function, similar to human dRTA patients.

Renal proximal tubules are sensitive to metabolic acidosis

This paper shows that proximal tubules are sensitive to metabolic acidosis, leading to trafficking defects and lysosomal damage, and that bicarbonate therapy can prevent these issues.