Sebastian Bachmann

The paper identifies three distinct cell types in thick ascending limb cells across species, each with unique potassium channel and claudin expression patterns that influence cation transport.

This paper shows that proximal tubules are sensitive to metabolic acidosis, leading to trafficking defects and lysosomal damage, and that bicarbonate therapy can prevent these issues.

This study uses single-nuclei transcriptomics to analyze human kidney injury responses, identifying four injury-associated cell states and showing similar gene expression changes between AKI patients with and without COVID-19.

The paper describes a methodology for preparing large-scale digitization samples to enable automated electron microscopy, improving throughput and reducing bias in ultrastructural analysis.