Christian Franke

Democratizing three-dimensional surface phenotyping: an open structured-light platform reveals and removes the projection bias in biological imaging

The paper introduces an open structured-light platform to measure 3D surface phenotypes, revealing that projection bias significantly underestimates surface area and can confound phenotype comparisons.

UV photogrammetry for transparent and composite surfaces

This paper introduces UV speckle photogrammetry to enable 3D reconstruction of transparent and composite surfaces, achieving high accuracy and completeness.

Cell-Type Resolved Protein Atlas of Brain Lysosomes Identifies SLC45A1-Associated Disease as a Lysosomal Disorder

The paper creates a cell-type-specific lysosome protein atlas in the brain, identifies SLC45A1 as a neuron-specific lysosomal protein, and shows its role in lysosomal function and neurodegeneration.

NanTex enables computational multiplexing and phenotyping of organelles across super-resolution modalities

NanTex enables multiplexing and phenotyping of organelles using nanotexture descriptors from single-channel super-resolution microscopy data across multiple modalities.

Applying telecentric stereo 3D-measurement to small Lepidopterans - bridging the macro and the microscale with isotropic micrometer resolution

This paper develops a telecentric stereo 3D-measurement system for high-precision, isotropic micrometer-resolution imaging of small Lepidoptera moths.

A primary sensory cortical interareal feedforward inhibitory circuit for tacto-visual integration

The paper shows that tactile stimulation suppresses visual activity in primary visual cortex via interneurons receiving input from somatosensory cortex in mice.