Author

Zan Luthey-Schulten

University of Illinois Urbana-Champaign

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Synthetic Biology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:gene regulatory network inference· 2 Assay:proteomics· 2 Organism:C. elegans· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Assay:long-read sequencing· 1 Assay:metagenomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Angad P. MehtaiD· 2 shared Aaron ChaniD· 1 shared Abner T. ApsleyiD· 1 shared Amar D. ParvateiD· 1 shared August GeorgeiD· 1 shared Christopher J. FieldsiD· 1 shared Connah JohnsoniD· 1 shared D. H. Kim· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersSynthetic Biology

Angad P. MehtaORCID

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2 papers

Recent·Most cited

Full-length transcriptomics and proteomics reveal how genome minimization reshapes gene expression in synthetic bacteria

Enguang Fu, Troy A. Brier, Jason E. Cournoyer, Sage Glass, Yang-le Gao, Yanbao Yu, Zane R. Thornburg, Karrie C. Goglin, Gavin John, Tiana Mamaghani, Sujata Shivakumar, Abner T. Apsley, Christopher J. Fields, Angad P. Mehta, John I. Glass, Zan Luthey-Schulten

The paper characterizes RNA and protein expression in synthetic bacteria Syn1.0 and Syn3A, showing genome minimization alters gene expression and resource allocation.

bioRxiv · Sep 10, 2026 · PreprintSynthetic Biology

Spatiotemporal 4D Whole-cell Modeling of a Minimal Autotroph Reveals Central Carbon Metabolism Regulated Locally by Protein Megacomplexes via Post-translational Modifications under Light Disturbance

Connah Johnson, Aaron Chan, Jordan C. Rozum, August George, Amar D. Parvate, Pavlo Bohutskyi, D. H. Kim, Song Feng, Zachary Johnson, Natalie Sadler, Marci Garcia, Xiaolu Li, Jesse B. Trejo, Ruonan Wu, William Sineath, , Margaret S. Cheung

The paper develops a 4D whole-cell model of Prochlorococcus marinus MED4 to show how spatial organization and redox PTMs regulate carbon fixation under light disturbance.

Biophysical Journal · Aug 26, 2026Peer-reviewedSystems Biology