Yoav Livneh

Thalamo-insular basis for updating physiological needs

This study shows that thalamic inputs to the insular cortex update representations of physiological needs like thirst and hunger, and that inhibiting these inputs prevents such updates.

A cortical basis for perception of internal gut sensations

Mice can report optogenetic activation of vagal gut mechanosensory neurons; insular cortex encodes perceptual report and causally affects detection only in a difficult psychophysics task, not simple detection.

Insular cortex predictions regulate glucose homeostasis

The paper shows that insular cortex activity predicts glucose homeostasis by driving anticipatory insulin release and metabolic regulation.

Dynamic Ribosomal RNA Methylation Regulates Translation in the Hematopoietic System and is Essential for Stem Cell Fitness

The paper identifies rRNA methylation dynamics as a mechanism regulating translation efficiency and HSC fitness during hematopoietic differentiation.

Stereotyped goal-directed manifold dynamics in the insular cortex

This study uses unsupervised machine learning to analyze insular cortex activity in mice during goal-directed behaviors, finding stereotyped neuronal manifold dynamics that predict trial outcomes across different motivational states.