Author

Malathi Kandarpa

University of MichiganORCID 0000-0002-0440-4964Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:proteomics· 1

Frequent Co-Authors

Moshe TalpaziD· 2 shared Aaron M. RobidaiD· 1 shared Amanpreet KauriD· 1 shared Andrew J. Alt· 1 shared Bryndon J. Oleson· 1 shared Erin M. KroppiD· 1 shared Grace PagnuccoiD· 1 shared Harini DesikaniD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersImmunology

Moshe TalpazORCID

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2 papers

Recent·Most cited

Effects of Calreticulin Mutations on HLA Class I Expression in Myeloproliferative Neoplasms

Amanpreet Kaur, Harini Desikan, Grace Pagnucco, Malathi Kandarpa, Moshe Talpaz, Malini Raghavan

This study examines how CALR mutations affect HLA class I expression in MPN cells, finding allele-dependent effects and correlations with tapasin.

bioRxiv · Jun 24, 2025 · PreprintImmunology

Identification of Omaveloxolone as An Endoplasmic Reticulum Associated Degradation Inhibitor That Induces Early Apoptotic Signaling in Multiple Myeloma

Erin M. Kropp, Sho Matono, Olivia Y. Wang, Aaron M. Robida, Malathi Kandarpa, Jineigh L. Grant, Bryndon J. Oleson, Andrew J. Alt, Moshe Talpaz, Matthew James Pianko, Qing Li

This paper identifies omaveloxolone as an ERAD inhibitor that induces apoptosis in multiple myeloma cells through caspase 8 and DISC signaling.

bioRxiv · Apr 2, 2025 · PreprintCell Biology