Moshe Talpaz

This study examines how CALR mutations affect HLA class I expression in MPN cells, finding allele-dependent effects and correlations with tapasin.

This paper identifies omaveloxolone as an ERAD inhibitor that induces apoptosis in multiple myeloma cells through caspase 8 and DISC signaling.

This study identifies a therapeutic vulnerability in POU2F-POU2AF-driven cancers by showing that targeting the mSWI/SNF complex with a PROTAC degrader reduces tumor growth in preclinical models.