Author

Tom Houben

Centre National de la Recherche ScientifiqueORCID 0000-0002-0441-3166Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

Amélie BarthelemyiD· 1 shared Ashleigh Jimenez-Lemus· 1 shared Emiel P. C. van der VorstiD· 1 shared Erik A.L. BiesseniD· 1 shared Eugeniu VasileiD· 1 shared Frank W. PfriegeriD· 1 shared Izabela‐Cristina StancuiD· 1 shared Jill Grondelaers· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperNeuroscience

Amélie BarthelemyORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

The lipid landscape shapes the immunomodulatory potential of fluoxetine in macrophages

Jill Grondelaers, Ashleigh Jimenez-Lemus, Lieve Temmerman, Erik A.L. Biessen, Ronit Shiri‐Sverdlov, Emiel P. C. van der Vorst, Tom Houben

This study shows that the macrophage lipid landscape influences the immunomodulatory effects of fluoxetine, with lipid alterations affecting its anti-inflammatory potential in treatment-resistant depression.

bioRxiv · Aug 28, 2026 · PreprintImmunology

Glial contribution to cyclodextrin-mediated reversal of cholesterol accumulation in murine NPC1-deficient neurons in vivo

Amélie Barthelemy, Valérie Demais, Izabela‐Cristina Stancu, Eugeniu Vasile, Tom Houben, Michaël Reber, Valentina Pallottini, Martine Perraut, Sophie Reibel, Frank W. Pfrieger

This study investigates how cyclodextrin reverses cholesterol accumulation in NPC1-deficient neurons by involving glial cells in lipid removal.

Neurobiology of Disease · Aug 5, 2021Peer-reviewedNeuroscience