Author

Lieve Temmerman

Maastricht University Medical CentreORCID 0000-0003-1102-0640Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

Erik A.L. BiesseniD· 2 shared Alberto BardelliiD· 1 shared Ashleigh Jimenez-Lemus· 1 shared Carmen López‐IglesiasiD· 1 shared Emiel P. C. van der VorstiD· 1 shared Erwin Wijnands· 1 shared Frank VerhaegeniD· 1 shared Jill Grondelaers· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersImmunology

Erik A.L. BiessenORCID

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2 papers

Recent·Most cited

The lipid landscape shapes the immunomodulatory potential of fluoxetine in macrophages

Jill Grondelaers, Ashleigh Jimenez-Lemus, Lieve Temmerman, Erik A.L. Biessen, Ronit Shiri‐Sverdlov, Emiel P. C. van der Vorst, Tom Houben

This study shows that the macrophage lipid landscape influences the immunomodulatory effects of fluoxetine, with lipid alterations affecting its anti-inflammatory potential in treatment-resistant depression.

bioRxiv · Aug 28, 2026 · PreprintImmunology

Adrenergic signaling induces a pro-tumorigenic B cell state in colorectal cancer

Meike S. Thijssen, Simone L. Schonkeren, Linde Coolkens, Yuchi Zou, Lieve Temmerman, Joëlle de Vaan, Musa Idris, Jorunn Vranken, Kim Wouters, Nathalie Vaes, Marion J. Gijbels, Sharon Scardellato, Erwin Wijnands, Willine J. van de Wetering, Frank Verhaegen, , Veerle Melotte

This study shows adrenergic signaling promotes a pro-tumorigenic B cell state in colorectal cancer by altering their transcriptome and function, linking neuronal activity to immune responses and patient survival.

bioRxiv · Jan 23, 2026 · PreprintCancer Biology