Erik A.L. Biessen

This study shows that the macrophage lipid landscape influences the immunomodulatory effects of fluoxetine, with lipid alterations affecting its anti-inflammatory potential in treatment-resistant depression.

The paper identifies iron deposition as a distinct phase of intraplaque hemorrhage, associated with inflammation and remodeling, through transcriptomic, histological, and metabolic analyses of human atherosclerotic plaques.

This study shows adrenergic signaling promotes a pro-tumorigenic B cell state in colorectal cancer by altering their transcriptome and function, linking neuronal activity to immune responses and patient survival.

This paper shows that miR-26b deficiency worsens MASH in mice, and that miR-26b mimic-loaded LNPs can reverse these effects.

This study shows that pharmacological depletion of microglia prevents short-term memory impairment in Ang II-induced hypertension.