Author

Malay Mandal

University of ChicagoORCID 0000-0002-0451-3896Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 2 Bioinformatics· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Research Focus:chromatin & epigenetic regulation· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Assay:ChIP-seq· 2 Research Focus:development & morphogenesis· 2 Approach:experimental assay· 2 Approach:statistical model· 2

Frequent Co-Authors

Marcus R. ClarkiD· 2 shared Margaret VeselitsiD· 2 shared Mark Maienschein‐ClineiD· 2 shared Nathaniel WrightiD· 2 shared Damien ReynaudiD· 1 shared Domenick E. KennedyiD· 1 shared Durga KrishnamurthyiD· 1 shared Erik P. KarmeleiD· 1 shared

Activity by Year

2023-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersImmunology

Marcus R. ClarkORCID

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Author profile →

4 papers

Recent·Most cited

BRWD1 establishes epigenetic states for germinal center initiation, maintenance, and function

Nathaniel Wright, Domenick E. Kennedy, Junting Ai, Margaret Veselits, Mary Attaway, Young me Yoon, Madeleine S. Durkee, Jacob Veselits, Mark Maienschein‐Cline, Malay Mandal, Marcus R. Clark

This study shows BRWD1 is essential for maintaining epigenetic states in germinal center B cells, affecting their function and subset identity.

Nature Communications · Sep 10, 2026Peer-reviewedImmunology

Ddx3x regulates B-cell development and immunoglobulin rearrangement in mice

Ke Liu, Durga Krishnamurthy, Jasmine A. Tuazon, Eshana Mukhopadhyay, Harsha Seelamneni, Erik P. Karmele, Omer A. Donmez, Thomas Perlot, Michelle Foong-Sobis, Rebekah A. Karns, Malay Mandal, Damien Reynaud, Leah Claire Kottyan, Matthew T. Weirauch, Wen-Hai Shao, , Stephen N. Waggoner

This study shows that Ddx3x is essential for B-cell development in mice, with loss leading to developmental blocks and defects in immunoglobulin rearrangement.

bioRxiv · Nov 28, 2025 · PreprintImmunology

Jk DNA GAGA MOTIFS ARE REQUIRED FOR LOCAL NUCLEOSOME REMODELING AND Vk-Jk RECOMBINATION

Margaret Veselits, Kaitlin C. McLean, Nathaniel Wright, Michael K. Okoreeh, Mark Maienschein‐Cline, Malay Mandal, Marcus R. Clark

This study shows that GAGA motifs 5' to Jk RSSs are essential for nucleosome positioning and Vk-Jk recombination in mice.

bioRxiv · Jan 21, 2025 · PreprintCell Biology

A divide and conquer approach (DACA) to predict high fidelity structure of large multidomain protein BRWD1

Rajkrishna Mondal, Malay Mandal, Tapobrata Lahiri

This paper predicts the high-fidelity structure of the large multidomain protein BRWD1 using a divide and conquer approach with fragment-based modeling and integration of AlphaFold and RoseTTAFold outputs.

bioRxiv · Jul 10, 2023 · PreprintBioinformatics