Author

Antoine Aze

Centre National de la Recherche Scientifique

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Assay:DNA methylation· 1 Organism:Drosophila· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Domenico MaioranoiD· 2 shared Tom EggeriD· 2 shared Adam Aissanou· 1 shared Alain ChavanieuiD· 1 shared Angelos ConstantinouiD· 1 shared Aurore SiegfriediD· 1 shared Benoît BordignoniD· 1 shared Cédric Hassen‐KhodjaiD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCancer Biology

Domenico MaioranoORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

A non-catalytic function for Rad18 in sustaining glioblastoma proliferation

Nour El Houda Benbahouche, Antoine Aze, Aurore Siegfried, Lenka Štefančíková, Chames Kermi, Jean‐Marc Pascussi, Julie Pannequin, Jérôme Moreaux, Tom Egger, Alain Chavanieu, Jean‐Philippe Hugnot, Marie‐Bernadette Delisle, Elizabeth Cohen‐Jonathan Moyal, Emmanuelle Uro‐Coste, Domenico Maiorano

This study identifies a non-catalytic role for Rad18 in sustaining glioblastoma proliferation and proposes it as a therapeutic target.

Cell Reports · Jul 1, 2026Peer-reviewedCancer Biology

TopBP1 biomolecular condensates: a new therapeutic target in advanced-stage colorectal cancer.

Laura Morano, Nadia Vié, Adam Aissanou, Tom Egger, Antoine Aze, Solène Fiachetti, Benoît Bordignon, Cédric Hassen‐Khodja, Hervé Seitz, Louis-Antoine Milazzo, Véronique Garambois, Laurent Chaloin, Nathalie Bonnefoy, Céline Gongora, Angelos Constantinou, Jihane Basbous

This study identifies TopBP1 condensation inhibitors, showing AZD2858 disrupts ATR signaling and synergizes with chemotherapy in colorectal cancer.

eLife · Oct 21, 2025Peer-reviewedCancer Biology

Translesion DNA synthesis-driven mutagenesis in very early embryogenesis of fast cleaving embryos

Elena Lo Furno, Isabelle Busseau, Antoine Aze, Claudio Lorenzi, Cima Saghira, Matt Christopher Danzi, Stephan L. Zuchner, Domenico Maiorano

The paper investigates mutagenesis in early embryos of Xenopus and Drosophila, showing that translesion DNA synthesis (TLS) driven by Rad18 contributes to high mutation rates.

Nucleic Acids Research · Dec 22, 2021Peer-reviewedDevelopmental Biology