Author

Guangzu Zhao

Australian Institute of Tropical Health and MedicineORCID 0000-0002-0541-3125Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 3 Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:host-pathogen & immune response· 2 Assay:multiome· 1 Assay:protein sequence· 1

Frequent Co-Authors

Andreas KupziD· 3 shared Harindra Darshana SathkumaraiD· 3 shared Julia SeifertiD· 3 shared Munish PuriiD· 3 shared Socorro Miranda‐HernandeziD· 3 shared Ana Maria Valencia‐HernandeziD· 2 shared Andrew CalcinoiD· 1 shared István TóthiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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3 shared papersImmunology

Andreas KupzORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

ImmunologybioRxivPreprintJul 24, 2026

mRNA-based prime-and-pull vaccination combines benefits of subcutaneous and mucosal BCG vaccination

Ana Maria Valencia‐Hernandez, Guangzu Zhao, Julia Seifert…·Andreas Kupz

This paper describes an mRNA-based prime-and-pull vaccination strategy that combines subcutaneous BCG vaccination with mucosal mRNA delivery to achieve protective immunity against tuberculosis with improved safety.

DOI 10.64898/2026.07.21.739464

mousemultiome

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ImmunologybioRxivPreprintJul 8, 2026

Pulmonary delivery of antigen-enhanced BCG overcomes safety barriers in immunocompromised hosts and protects against TB in the absence of adaptive immunity.

Harindra Darshana Sathkumara, Guangzu Zhao, Andrew Calcino…·Andreas Kupz

This study shows that pulmonary delivery of ESAT-6-secreting BCG strains improves safety and protection against TB in immunocompromised mice, independent of adaptive immunity.

DOI 10.64898/2026.07.05.736631

mouseexperimental assay

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MicrobiologySmallPeer-reviewedJan 5, 2025

A modular self-assembling and self-adjuvanting multiepitope peptide nanoparticle vaccine platform to improve the efficacy and immunogenicity of BCG

Guangzu Zhao, Harindra Darshana Sathkumara, Socorro Miranda‐Hernandez…·Andreas Kupz

This paper develops a modular peptide nanoparticle vaccine platform that enhances BCG's immunogenicity and efficacy in a murine TB model by over 5-fold.

8 citations

mouseprotein sequence

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