James Zhen

This study characterizes Hb-filled vesicles (HbVs) in Plasmodium falciparum, identifying their morphology, molecular composition, and a Rab-regulatory component involved in endosomal transport.

This paper introduces a pipeline for high-resolution cryo-ET imaging using square electron beams, demonstrating improved resolution and field-of-view by reducing radiation damage and overlap.

The paper determines the cryoEM structure of PfATP4, revealing a novel apicomplexan-specific binding partner, PfABP, which may guide the design of new inhibitors.

This study uses cryoET and deep learning to reveal structural differences in the tegument and envelope of EBV and KSHV virions compared to other herpesviruses.

The paper reports cryoEM structures of endogenous 2-oxoglutarate and pyruvate dehydrogenase complexes from bovine kidney, revealing structural differences and insights into their organization.