Molecular BiologybioRxivPreprint
Repurposing tRNA isodecoders for non-canonical functions via tRNA cleavage
Nupur Bhatter, Vivek M. Advani, Yoshika Takenaka…·Pavel V. Ivanov
The paper shows that cleavage of tRNA isodecoders generates tRNA-derived RNAs (tDRs) with differential activities in mRNA reporter translation, suggesting a mechanism for repurposing tRNAs for non-canonical functions.
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