Author

Christian R. O. Bartling

University of CopenhagenORCID 0000-0002-0602-4738Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1 Organism:non-human primate· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1

Frequent Co-Authors

Kristian StrømgaardiD· 2 shared Amanda D. DueiD· 1 shared Anders DalbyiD· 1 shared Andrea SottiniiD· 1 shared Angela HoiD· 1 shared Benjamin SchuleriD· 1 shared Birthe Brandt KragelundiD· 1 shared Catarina B. FernandesiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersNeuroscience

Kristian StrømgaardORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

The SorCS2-derived macrocycle TT-P34 drives neuroprotection in animal models of neurodegeneration

Anders Dalby, Mathias Kaas Ollendorff, Johan Palmfeldt, Mads Graversgaard, Sanne Nordestgaard, Christian R. O. Bartling, Kasper Budolph, Neil Benson, Emily Roashan, Søren L. Pedersen, Heather Mortiboys, Larry C. Park, Simon Glerup, Kristian Strømgaard, Keld Fosgerau, Simon Mølgaard

The paper develops a SorCS2-derived macrocycle, TT-P34, which shows neuroprotective effects in animal models of neurodegeneration by enhancing mitochondrial function and reducing disease symptoms.

Acta Neuropathologica Communications · Aug 10, 2026Peer-reviewedNeuroscience

The importance of stereochemistry in the disorder-order continuum of protein-protein interactions

Estella A. Newcombe, Amanda D. Due, Andrea Sottini, Steffie Elkjær, Frederik Friis Theisen, Catarina B. Fernandes, Lasse Staby, Elise Delaforge, Christian R. O. Bartling, Inna Brakti, Katrine Bugge, Benjamin Schuler, Karen Skriver, Johan Gotthardt Olsen, Birthe Brandt Kragelund

The paper investigates the role of stereochemistry in disordered protein-protein interactions, finding that chirality is inconsequential in fully disordered complexes but essential when folding and binding are coupled.

Nature · Nov 27, 2024Peer-reviewedBiophysics

Tight control of the APP-Mint1 interaction in regulating amyloid production

Shawna M. Henry, Sabrina A. Kistler, Gavin D. Lagani, Christian R. O. Bartling, Dennis Özcelik, Vita Sereikaité, Kristian Strømgaard, Uwe Beffert, Angela Ho

This study investigates how altering the APP-Mint1 interaction affects amyloid-beta production and cellular dynamics in neurons.

Brain Research · Jul 25, 2023Peer-reviewedNeuroscience