The SorCS2-derived macrocycle TT-P34 drives neuroprotection in animal models of neurodegeneration
Anders Dalby, Mathias Kaas Ollendorff, Johan Palmfeldt, Mads Graversgaard, Sanne Nordestgaard, Christian R. O. Bartling, Kasper Budolph, Neil Benson, Emily Roashan, Søren L. Pedersen, Heather Mortiboys, Larry C. Park, Simon Glerup, Kristian Strømgaard, Keld Fosgerau, Simon Mølgaard
The paper develops a SorCS2-derived macrocycle, TT-P34, which shows neuroprotective effects in animal models of neurodegeneration by enhancing mitochondrial function and reducing disease symptoms.
Acta Neuropathologica Communications · Aug 10, 2026Peer-reviewedNeuroscience