M. Felicia Davatolhagh

This study examines age-related changes in neural and behavioural variability during a decision-making task in mice, finding increased neural variability and reduced variability quenching in specific brain regions.

The paper creates a 3D atlas of SST, PV, and TH interneurons in the mouse caudoputamen, revealing distinct spatial distributions across striatal territories.

This study examines how Nrxn1 loss-of-function affects prior utilization and neural dynamics in a mouse model of autism, revealing impaired decision-making and altered cortical activity.

Mice infer stimulus-side priors from recent choices; prior signals are decodable pre-stimulus in 24.0% to 30.2% of 242 brain regions, including early visual and motor areas.

The paper presents a brain-wide neural activity map from 621,733 neurons across 139 mice performing a decision-making task, showing how neural activity encodes task variables across brain regions.

The paper shows that mice with ASD-related mutations exhibit similar computational and neural anomalies in prior updating during decision-making.

This study evaluates the reproducibility of electrophysiological measurements across ten labs using standardized protocols and finds that variability in electrode targeting and statistical methods affects reproducibility.

This study identifies sex- and cell type-specific transcriptomic and behavioral effects of 16p11.2 hemideletion in mice, revealing distinct impacts on striatal circuits and locomotor behavior.

The paper shows that LTSIs in the dorsomedial striatum gate dopamine release via GABAB signaling during learning.

This study investigates how Neurexin1 mutations in specific brain circuits affect value-based decision-making and identifies neural mechanisms underlying cognitive dysfunction in neuropsychiatric disorders.

This study shows that Neurexin1 regulates synaptic strength specifically in striatal indirect pathway spiny neurons, but not in thalamic inputs.