Hervé Tettelin

This paper analyzes the genomic characteristics of Streptococcus agalactiae ST1010 strains, showing they share virulence genes with CC17 and have a subclade with high-level gentamicin resistance.

The paper shows that biofilm formation during pneumococcal colonization shapes humoral immunity and protection, with the first colonizing strain imprinting immune responses toward biofilm antigens.

This study examines metabolic changes in the lungs during Streptococcus pneumoniae infection, revealing shifts in metabolite levels and bacterial gene expression that correlate with disease progression.

This study shows Neisseria gonorrhoeae induces IL-10 secretion at the cervix via CEACAMs to prevent epithelial shedding and inflammation, enabling asymptomatic colonization.

This study identifies genetic changes in M. abscessus outbreak strains that lead to high imipenem resistance, suggesting carbapenem/{beta}-lactamase inhibitor combinations for treatment.

This paper introduces a streamlined method for marker-less allelic replacement in Streptococcus pneumoniae using a single transformation step, reducing complexity and false positives compared to traditional methods.

This study uses dual-species RNA-seq to analyze the transcriptional responses of Neisseria gonorrhoeae and human neutrophils during infection, revealing shared metabolic and immunologic processes.