Author

Samarchith P. Kurup

University of GeorgiaORCID 0000-0002-0640-0502Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Organism:mouse· 3 Research Focus:cell type annotation· 2 Research Focus:host-pathogen & immune response· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

Alex RosenbergiD· 2 shared Carson BowersiD· 2 shared Clyde Schmidt-SilvaiD· 2 shared Nana Appiah Essel Charles-ChessiD· 2 shared Anthony A. RubertoiD· 1 shared Bae-Hoon KimiD· 1 shared Boubacar TraoréiD· 1 shared Camila Marques-da-SilvaiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersMicrobiology

Alex RosenbergORCID

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3 papers

Recent·Most cited

A Suite of Eight Toxoplasma gondii Effectors Cooperates to Activate the Non-canonical NF-κB Pathway

Kenna E. Berg, Michael W. Panas, Samarchith P. Kurup, John C. Boothroyd, Alex Rosenberg

This paper shows that Toxoplasma gondii uses eight effectors to activate the non-canonical NF-κB pathway in host cells through a collaborative network.

mBio · Aug 28, 2026Peer-reviewedMicrobiology

Memory Regulatory T Cells Reprogram into Protective Tfh-like Effectors in Recurrent Malaria

Nana Appiah Essel Charles-Chess, Anthony A. Ruberto, Carson Bowers, Clyde Schmidt-Silva, Nyamekye Obeng-Adjei, Matthew R. Hansen, Disha BR Prasad, Alex Rosenberg, Boubacar Traoré, Kimberly D. Klonowski, Peter D. Crompton, Samarchith P. Kurup

The paper shows memory Tregs reprogram into protective Tfh-like cells during recurrent malaria, enhancing antibody responses and parasite control.

Nature Immunology · Jun 22, 2026Peer-reviewedImmunology

Type-I IFNs induce GBPs and lysosomal defense in hepatocytes to control malaria

Camila Marques-da-Silva, Clyde Schmidt-Silva, Carson Bowers, Nana Appiah Essel Charles-Chess, Cristina Samuel, Justine C. Shiau, Eui‐Soon Park, Zhongyu Yuan, Bae-Hoon Kim, Dennis E. Kyle, John T. Harty, John D. MacMicking, Samarchith P. Kurup

This study identifies two IFN-I-driven hepatocyte antimicrobial programs that control liver-stage malaria by inducing GBPs and lysosomal defense mechanisms.

Cell Host & Microbe · Apr 1, 2025Peer-reviewedImmunology