Sacha Psalmon

ALIGN: A modular framework for quantitative analysis of longitudinal development in Caenorhabditis elegans

ALIGN provides a modular framework for analyzing longitudinal development in C. elegans, enabling accurate segmentation, quality control, and motion correction across imaging conditions.

Temporal compression of gonadal growth preserves reproductive timing and soma-to-germline scaling under stress

This study shows that reproductive timing is preserved under stress through dynamic control of gonadal growth in C. elegans, maintaining reproductive-to-somatic size ratios.

The MAPK phosphatase VHP-1 buffers pharynx-to-body proportions against tissue-specific growth imbalance in C. elegans

The paper identifies VHP-1 as a buffer against pharynx-to-body growth imbalance in C. elegans by showing its role in modulating MAPK pathways under tissue-specific growth perturbations.

Teach your microscope how to print: Low-cost and rapid-iteration microfabrication for biology

This paper introduces a low-cost microfabrication method using 3D printing and repurposed microscopes for biological applications, achieving micrometer precision without clean room infrastructure.

Autophagy-dependent proteome remodelling and ribosome decline balance starvation survival and recovery speed in C. elegans

This study shows that autophagy-dependent loss of ribosomal proteins during starvation in C. elegans balances survival and recovery speed by affecting growth resumption.