Pierre‐François Roux

THE MULTIFUNCTIONAL PROTEIN E4F1 REGULATES MELANOCYTIC FUNCTIONS IN MICE THROUGH PROTEIN TRANSLATION AND MITF EXPRESSION

This study shows E4F1 regulates melanogenesis in mice by controlling protein translation and MITF expression through the ISR pathway.

Beyond chromatin accessibility: bulk ATAC-seq as an integrative assay to portray genomes and epigenomes

This study evaluates bulk ATAC-seq's ability to detect genomic variants, CNVs, and telomere repeats, showing its potential as an integrative tool for cancer research.

Escape From Oncogene-Induced Senescence is Controlled by POU2F2 and Memorized by Chromatin Scars

The paper identifies POU2F2 and chromatin scars as mechanisms enabling escape from oncogene-induced senescence and their potential as biomarkers in colorectal cancer.

E4F1 COORDINATES PYRUVATE METABOLISM AND THE ACTIVITY OF THE ELONGATOR COMPLEX TO ENSURE TRANSLATION FIDELITY DURING BRAIN DEVELOPMENT

AP-1 Imprints a Reversible Transcriptional Program of Senescent Cells

The paper identifies AP-1's role in shaping the epigenetic landscape of senescent cells and presents a hierarchical TF network model for senescence reprogramming.