Author

Lan Dang

Pennsylvania State UniversityORCID 0000-0002-8524-5140Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 3 Approach:experimental assay· 2 Assay:imaging· 2 Approach:statistical model· 2 Assay:cryo-EM· 1 Research Focus:database / resource· 1 Approach:deep learning· 1 Research Focus:dimensionality reduction· 1

Frequent Co-Authors

Wen JiangiD· 2 shared Amit SingeriD· 1 shared Carlos Óscar S. SorzanoiD· 1 shared David HerrerosiD· 1 shared David Silva-SáncheziD· 1 shared Eduardo R. Cruz-ChúiD· 1 shared Ellen D. ZhongiD· 1 shared Fei YeiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersBiophysics

Wen JiangORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Low-pass filtering revisited: ramped phase randomization for cryo-EM map comparison and data augmentation

Lan Dang, Wen Jiang

This paper introduces ramped phase randomization to improve cryo-EM map comparison and data augmentation by reducing fine-scale detail while preserving low-frequency content and enhancing machine learning performance.

bioRxiv · Nov 1, 2026 · PreprintBiophysics

WebCalEM: a browser-based tool for routine and accurate pixel size calibration in cryo-EM

Lan Dang, Zhiqing Wang, Sung Hyun Cho, Siduo Li, Geetanjali Chakraborty, Nahian Fyrose Fahim, Wen Jiang

WebCalEM provides a browser-based tool for accurate pixel size calibration in cryo-EM, eliminating installation barriers and enabling routine use.

Acta Crystallographica Section F Structural Biology Communications · Jul 15, 2026Peer-reviewedMolecular Biology

The Inaugural Flatiron Institute Cryo-EM Conformational Heterogeneity Challenge

Miro A. Astore, Geoffrey Woollard, David Silva-Sánchez, Wenda Zhou, Mykhailo Kopylov, Khanh Dao Duc, Roy R. Lederman, Yilai Li, Yi Zhou, Jing Yuan, Fei Ye, Quanquan Gu, Rémi Vuillemot, Slavica Jonić, Lan Dang, , Sonya M. Hanson

The paper presents a cryo-EM conformational heterogeneity challenge to evaluate and improve methods for analyzing molecular motions in heterogeneous samples.

bioRxiv · Jul 18, 2025 · PreprintBiophysics