Author

Casper Berger

Rosalind Franklin InstituteORCID 0000-0002-0705-3194Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:cryo-EM· 1 Organism:E. coli· 1 Approach:experimental assay· 1 Assay:imaging· 1 Approach:machine learning (classical)· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Maud DumouxiD· 2 shared Elaine M. L. HoiD· 1 shared Helena WatsoniD· 1 shared James Boris GilchristiD· 1 shared James H. NaismithiD· 1 shared Luı́s M. A. PerdigãoiD· 1 shared Mark BashamiD· 1 shared Michael GrangeiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersMolecular Biology

Maud DumouxORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Adaptive Milling: imaging feedback-driven automated fabrication of consistently thin cryo-lamellae

Thomas S. Glen, Thomas M. Fish, Elaine M. L. Ho, Patrick Cleeve, Luı́s M. A. Perdigão, Nadisha Gamage, Ravi Teja Ravi, James Boris Gilchrist, Michele C. Darrow, Mark Basham, Maud Dumoux, Casper Berger

This paper introduces Adaptive Polishing, a machine learning-driven method for improving the consistency and thinness of cryo-lamellae during focused ion beam milling.

bioRxiv · Sep 22, 2026 · PreprintMolecular Biology

Xenon plasma focused ion beam lamella fabrication on high-pressure frozen specimens for structural cell biology

Casper Berger, Helena Watson, James H. Naismith, Maud Dumoux, Michael Grange

This paper demonstrates xenon plasma focused ion beam milling for preparing high-pressure frozen specimens, achieving a 4.0 Å E. coli ribosome structure with minimal structural damage beyond 45 nm.

Nature Communications · Mar 7, 2025Peer-reviewedBiochemistry