BioengineeringbioRxivPreprint
Coordinated Tuning of Ionizable Lipids and Formulation Redirects mRNA Vaccines Toward Lymphoid-Specific CD4+ T Cell Immunity
Yeji Lee, Yelim Choi, Seongryong Kim…·Hyukjin Lee
This study shows that modifying ionizable lipids and formulation parameters of mRNA vaccines can enhance CD4+ T cell immunity and improve vaccine efficacy.
DOI 10.64898/2026.04.16.719092