Author

Reynold Yu

National Institutes of HealthORCID 0000-0002-8093-254XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:statistical model· 4 Assay:bulk RNA-seq· 3 Research Focus:genome assembly· 2 Organism:human· 2 Organism:non-human primate· 2 Assay:ATAC-seq· 1 Research Focus:cell type annotation· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Andreas D. BaxevanisiD· 2 shared Abhinav SuriD· 1 shared Alberto M. RiveraiD· 1 shared Allan M. Carrillo‐BaltodanoiD· 1 shared Amanda M. KatzeriD· 1 shared Billie E. DaviesiD· 1 shared Changhong LiiD· 1 shared Diana E. StanescuiD· 1 shared

Activity by Year

2021-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersGenomics

Andreas D. BaxevanisORCID

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4 papers

Recent·Most cited

A chromosome-level reference genome for the colonial marine hydrozoan Podocoryna americana

E. Sally Chang, Michael T. Connelly, Matthew K. Travert, Sofia N. Barreira, Alberto M. Rivera, Amanda M. Katzer, Reynold Yu, Paulyn Cartwright, Andreas D. Baxevanis

This paper presents a chromosome-level genome assembly for Podocoryna americana, revealing gene family expansions and contractions compared to other cnidarians.

G3 Genes Genomes Genetics · Jun 25, 2026Peer-reviewedGenomics

A chromosome-level assembly and functional genomic resources for the model annelid Capitella teleta

Billie E. Davies, Paul Gonzalez, Abhinav Sur, Jingcheng Wei, Tom Frankish, Jimena Montagne, Allan M. Carrillo‐Baltodano, Kero Guynes, Yan Liang, Rory D. Donnellan, R. Travis Moreland, Sumeeta Singh, Suiyuan Zhang, Reynold Yu, Tyra G. Wolfsberg, , José María Martín-Durán

The paper presents a chromosome-level genome assembly and functional genomic resources for Capitella teleta, improving upon an outdated reference and enabling better analysis of multi-omic data.

Genome Biology and Evolution · Feb 24, 2026Peer-reviewedGenomics

Impaired Lef1 activation accelerates iPSC-derived keratinocytes differentiation in Progeria

Xiaojing Mao, Zheng‐Mei Xiong, Huijing Xue, Markus A. Brown, Yantenew G. Gete, Reynold Yu, Linlin Sun, Kan Cao

This study shows that impaired Lef1 activation in HGPS iPSCs accelerates keratinocyte differentiation, and base editing partially rescues this phenotype.

International Journal of Molecular Sciences · May 14, 2022Peer-reviewedDevelopmental Biology

PDX1 directs a core developmentally and evolutionarily conserved gene program in the pancreatic islet

Xiaodun Yang, Jeffrey C. Raum, Junil Kim, Reynold Yu, Juxiang Yang, Gabriella Rice, Changhong Li, Kyoung‐Jae Won, Doris A. Stoffers, Diana E. Stanescu

The paper identifies a core set of developmentally and evolutionarily conserved PDX1-bound genes in mouse and human pancreas development, showing stable PDX1 binding across ages with context-dependent regulatory roles.

bioRxiv · Feb 28, 2021 · PreprintDevelopmental Biology