Author

Hui Xie

BC Cancer Agency

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:proteomics· 2 Approach:statistical model· 2 Organism:bacteria (other)· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Andong Song· 1 shared Anne M. HaegertiD· 1 shared Augustin LunaiD· 1 shared Azin SayadiD· 1 shared Benjamin G. NeeliD· 1 shared Chris SanderiD· 1 shared Colin C. CollinsiD· 1 shared Doğancan ÖzturaniD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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1 shared paperBiochemistry

Andong Song

Author profile →

3 papers

Recent·Most cited

Longitudinal single-cell RNA sequencing of a neuroendocrine transdifferentiation model reveals transcriptional reprogramming in treatment-induced neuroendocrine prostate cancer

Funda Sar, Hee Chul Chung, Yen‐Yi Lin, Dong Lin, Tunç Morova, Anne M. Haegert, Stanislav V. Volik, Robert H. Bell, Stéphane LeBihan, Doğancan Özturan, Hui Xie, Xin Dong, Rebecca Wu, Jing Li, Hsing‐Jien Kung, , Colin C. Collins

This study uses longitudinal scRNA-seq to track neuroendocrine transdifferentiation in a prostate cancer model, identifying transcriptional changes and key regulators during treatment-induced NEPC progression.

Genome Medicine · Oct 28, 2026Peer-reviewedCancer Biology

THA_1941 from Thermosipho africanus: A Thermostable β-1,3-Glucan Phosphorylase for Efficient β-1,3-Glucan Synthesis

Guotao Mao, Jin Yu, Junhan Lin, Ming Song, Zengping Su, Hui Xie, Hognsen Zhang, Hongge Chen, Andong Song

This paper identifies THA_1941 from Thermosipho africanus as a thermostable β-1,3-glucan phosphorylase capable of efficiently synthesizing β-1,3-glucan using glucose as a primer.

bioRxiv · Apr 5, 2025 · PreprintBiochemistry

Proteomic Dynamics of Breast Cancers Identifies Potential Therapeutic Protein Targets

Rui Sun, Yi Zhu, Azin Sayad, Weigang Ge, Augustin Luna, Shuang Liang, Luis Tobalina Segura, Vinodh N. Rajapakse, YU Chen-huan, Huanhuan Zhang, Jie Fang, Fang Wu, Hui Xie, Julio Sáez-Rodríguez, Huazhong Ying, , Ruedi H. Aebersold

This study identifies a 24-protein panel distinguishing TNBC from other breast cancers and shows proteomics improves drug sensitivity predictions.

bioRxiv · Jun 3, 2022 · PreprintSystems Biology