Author

Elias Spiliotopoulos

Oregon Health & Science UniversityORCID 0000-0002-8522-2459Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Developmental Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Research Focus:differential expression· 3 Approach:experimental assay· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Approach:deep learning· 1

Frequent Co-Authors

Thuy T. M. NgoiD· 3 shared Aaron Reid DoeiD· 1 shared Breeshey Roskams-HieteriD· 1 shared Bryana Godfrey· 1 shared C. Ward KirschbaumiD· 1 shared Cécile Riviere-CazauxiD· 1 shared Charlotte WeixeliD· 1 shared Daniel B. HerrickiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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3 shared papersCancer Biology

Thuy T. M. NgoORCID

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3 papers

Recent·Most cited

CSF-Seq enables transcriptome-wide profiling of cerebrospinal fluid and identifies prognostic signature of leptomeningeal disease

Maxine C. Umeh-Garcia, Giuseppe Barisano, Pablo Nunez Perez, Thy Trang Hoang Trinh, Rukayat Taiwo, Daniel B. Herrick, Meaghen Roy-O'Reilly, Seunghyun Lee, Elias Spiliotopoulos, Charlotte Weixel, Georgiana Burnside, Bryana Godfrey, Yi Zhang, Sophia B. Chernikova, Sofia M. Tosoni, , Melanie Hayden Gephart

CSF-Seq profiles cerebrospinal fluid transcriptomes to identify a prognostic gene signature for leptomeningeal disease.

bioRxiv · May 26, 2026 · PreprintCancer Biology

Loss of cell cycle gatekeeping by 1 CNOT3 impairs hematopoietic stem and progenitor cell division and repopulating activity

Katie A. Yuen, Thilelli Taibi, Quang Anh Hoang, Marty Yue, Zongmin Liu, Effat Habibi, Elias Spiliotopoulos, Niveditha Ramkumar, Nick Nation, Glenn Edin, Thuy T. M. Ngo, Ly Vu

This study shows that CNOT3 deletion in HSCs causes anemia, reduced bone marrow cellularity, and impaired hematopoietic reconstitution.

bioRxiv · Oct 23, 2025 · PreprintDevelopmental Biology

Selective enrichment of plasma cell-free messenger RNA in cancer-associated extracellular vesicles

Hyun Ji Kim, Matthew J. Rames, Florian Goncalves, C. Ward Kirschbaum, Breeshey Roskams-Hieter, Elias Spiliotopoulos, Joséphine Briand, Aaron Reid Doe, Joseph Estabrook, Josiah T. Wagner, Emek Demir, Gordon Brent Mills, Thuy T. M. Ngo

The paper analyzes cf-mRNA in EVs and non-vesicular carriers from cancer patients and healthy donors, finding EVs selectively enrich cf-mRNA associated with specific biological pathways.

Communications Biology · Aug 29, 2023Peer-reviewedGenomics