Multimodal PET Defines a Goldilocks Thermal Window for Focused Ultrasound Ablation and Immunotherapy Combinations
Zehra E.F. Demir, Thomas Sherlock, Matthew R. DeWitt, Pouria Talebibarmi, Christian Palacios-Gomez, Alexander L. Klibanov, Kiel D. Neumann, SHAYN M. PEIRCE, Matthew J. Lazzara, Jonathan R. Lindner, Jiang He, Bijoy Kundu, Natasha Sheybani
This paper identifies an optimal thermal dose for focused ultrasound ablation that balances tumor destruction with immunotherapy access using multimodal PET imaging.
bioRxiv · Jun 11, 2026 · PreprintBioengineering