Daiji Okamura

PantheonOS introduces a multi-agent framework for automated genomics analysis, achieving super-human performance in batch correction and gene panel selection across diverse biological tasks.

This study identifies vitronectin as a key extracellular matrix protein that maintains a proliferative, differentiation-resistant state in myogenic cells by suppressing differentiation and sustaining proliferation through integrin vβ3 signaling.

This study establishes co-cultures of embryonic and extraembryonic stem cells to study lineage crosstalk during early mammalian development, revealing growth inhibition of pluripotent cells by extraembryonic endoderm cells.