Author

Cheng‐Sheng Lee

Brandeis UniversityORCID 0000-0002-0765-2410Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 2 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:yeast· 3 Approach:experimental assay· 2 Approach:statistical model· 1 Research Focus:variant calling· 1

Frequent Co-Authors

James E. HaberiD· 3 shared Allison MazzellaiD· 1 shared David P. WatermaniD· 1 shared Felix Y. ZhouiD· 1 shared Justin SmithiD· 1 shared Kevin LiiD· 1 shared Kevin M. Orsley· 1 shared Kevin R. RoyiD· 1 shared

Activity by Year

2017-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersGenetics

James E. HaberORCID

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3 papers

Recent·Most cited

Dissecting quantitative trait nucleotides by saturation genome editing

Kevin R. Roy, Justin Smith, Shengdi Li, Sibylle Chantal Vonesch, Michelle Nguyen, Wallace T. Burnett, Kevin M. Orsley, Cheng‐Sheng Lee, James E. Haber, Robert P. St.Onge, Lars Michael Steinmetz

The paper develops MAGESTIC 3.0, a CRISPR-based system for genome-wide variant installation in yeast, revealing missense variants and multiple causal variants in quantitative trait loci across environmental conditions.

bioRxiv · Feb 2, 2024 · PreprintGenetics

Live cell monitoring of double strand breaks in S. cerevisiae

David P. Waterman, Felix Y. Zhou, Kevin Li, Cheng‐Sheng Lee, Michael Tsabar, Vinay V. Eapen, Allison Mazzella, James E. Haber

The paper uses fluorescent markers to study DSB formation and repair dynamics in yeast, finding that DSB foci coalesce and dissociate without requiring Rad2 protein.

PLoS Genetics · Mar 1, 2019Peer-reviewedMolecular Biology

Position Effects Influencing Intrachromosomal Repair of a Double-Strand Break in Budding Yeast

Ruoxi W. Wang, Cheng‐Sheng Lee, James E. Haber

The paper investigates how the location of a donor sequence and centromere anchoring affect intrachromosomal repair of a double-strand break in budding yeast.

PLoS ONE · Jul 11, 2017Peer-reviewedGenetics