Yosra Berrouayel

Transcriptomic profile of embryoid bodies under hypoxia at single cell level

The paper generates a single-cell transcriptomic dataset of murine embryoid bodies under hypoxia and normoxia to study oxygen's impact on lineage specification and cellular heterogeneity during early development.

VCAN is essential for ERK5-driven tumorigenesis in soft tissue sarcoma

This study identifies VCAN as a novel transcriptional target of ERK5 and shows its essential role in ERK5-driven tumorigenesis in soft tissue sarcoma.

Enhancing TFEA.ChIP with ENCODE Regulatory Maps for Generalizable Transcription Factor Enrichment

The paper improves TFEA.ChIP by integrating ENCODE regulatory maps, enhancing accuracy in identifying transcription factor enrichment from gene expression data.

Intermittent Hypoxia Drives Early Metabolic Dysfunction in Brown Adipose Tissue

This study shows intermittent hypoxia impairs brown adipose tissue function through molecular and morphological changes, preceding systemic metabolic dysfunction in mice.

Bhlhe40 limits proliferation and prevents excessive angiogenesis in mouse embryoid bodies under hypoxia