Author

Ke Ning

University of SheffieldORCID 0000-0002-0771-1134Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 1 Genomics· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:gene regulatory network inference· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Approach:Bayesian inference· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

Cleide Dos Santos SouzaiD· 2 shared Ilaria GranataiD· 2 shared Laura FerraiuoloiD· 2 shared Mario Rosario GuarracinoiD· 2 shared Matthew R. LiveseyiD· 2 shared Pamela J. ShawiD· 2 shared Adriano ChiòiD· 1 shared Alexander J. WhitworthiD· 1 shared

Activity by Year

2021-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersGenomics

Cleide Dos Santos SouzaORCID

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3 papers

Recent·Most cited

GenomicsNeuronPeer-reviewedJan 18, 2022

Genome-wide Identification of the Genetic Basis of Amyotrophic Lateral Sclerosis

Sai Zhang, Johnathan Cooper‐Knock, Annika K K Weimer…·Michael P. Snyder

This study identifies 690 candidate ALS genes using a hierarchical Bayesian model, highlighting genetic convergence on the distal axon and functional significance in motor neurons.

116 citationstop 1%

humanwhole-genome sequencing

𝕏 PostBluesky

Systems BiologyMolecular NeurodegenerationPeer-reviewedAug 10, 2021

Safety and efficacy of C9ORF72-repeat RNA nuclear export inhibition in amyotrophic lateral sclerosis

Lydia M. Castelli, Luisa Cutillo, Cleide Dos Santos Souza…·Guillaume M. Hautbergue

This study shows that inhibiting SRSF1-dependent nuclear export of C9ORF72-repeat transcripts in ALS models protects neurons and identifies key RNA changes involved in disease.

34 citations

humanDrosophila

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Developmental BiologyDevelopmentPeer-reviewedMar 3, 2021

Defining the signalling determinants of a posterior ventral spinal cord identity in human neuromesodermal progenitor derivatives

Matthew Wind, Antigoni Gogolou, Ichcha Manipur…·Anestis Tsakiridis

This study identifies signalling pathways that guide the generation of posterior ventral spinal cord motor neurons from human pluripotent stem cells.

26 citations

humanbulk RNA-seq

𝕏 PostBluesky