Matthias Schlichting

Chronic mitochondrial fragmentation elicits a neuroprotective Warburg-like effect in Drosophila neurons

The paper shows that disrupting mitochondrial fusion in Drosophila neurons leads to a Warburg-like metabolic response that protects against neurodegeneration.

Dopamine and GPCR-mediated modulation of DN1 clock neurons gates the circadian timing of sleep

The paper identifies dopamine and GPCR-mediated modulation in Drosophila clock neurons that regulate sleep timing.

Two light sensors decode moonlight versus sunlight to adjust a plastic circadian/circalunidian clock to moon phase

The paper identifies two light sensors in Platynereis dumerilii that distinguish moonlight from sunlight to adjust a circadian clock to moon phase.

A transcriptomic taxonomy of Drosophila circadian neurons around the clock

The paper characterizes Drosophila circadian neurons using single-cell RNA sequencing, identifying 17 cell categories with time-dependent gene expression patterns.

Internal state configures olfactory behavior and early sensory processing in Drosophila larvae

This study shows how food deprivation alters olfactory behavior in Drosophila larvae by changing neural processing in the antennal lobe through state-dependent circuit dynamics.

Neuron-specific knockouts indicate the importance of network communication to Drosophila rhythmicity

The paper shows that network communication is important for Drosophila circadian rhythms, with specific neuron groups relying on it for period determination.

Light-mediated circuit switching in the Drosophila neuronal clock network

The paper identifies a light-mediated pathway in Drosophila that uses PDF-releasing lLNv neurons to adjust circadian rhythms to long day conditions.

Allatostatin C/AstC-R2 is a Novel Pathway to Modulate Circadian Activity Pattern in Drosophila

The paper identifies a novel AstC/AstC-R2 signaling pathway in Drosophila that modulates evening locomotor activity under short photoperiods.