Dingbang Ma

Transcriptomic and functional characterization indicate sexual dimorphism of discrete circadian neuron subtypes

The paper identifies sex-specific gene expression and synaptic connections in Drosophila circadian neurons, revealing molecular mechanisms underlying sexual dimorphism in circadian behavior.

Four SpsP neurons are an integrating sleep regulation hub in Drosophila

This study identifies four SpsP neurons in Drosophila as an integrating hub for sleep regulation through a circuit involving upstream and downstream synaptic partners.

Detecting Rhythmic Gene Expression in Single Cell Transcriptomics

This paper benchmarks circadian detection methods on single-cell RNAseq data and proposes a subsampling and harmonic regression strategy for detecting circadian genes.

Light and dopamine impact two circadian neurons to promote morning wakefulness

The paper identifies two circadian neurons in Drosophila that are influenced by light and dopamine to promote morning wakefulness.

Novel clock neuron subtypes regulate temporal aspects of sleep

The paper identifies novel clock neuron subtypes in Drosophila that regulate sleep timing through distinct projection patterns and a common receptor.

Neural connectivity molecules best identify the heterogeneous clock and dopaminergic cell types in the Drosophila adult brain

The paper identifies heterogeneous clock and dopaminergic cell types in Drosophila using single-cell sequencing and shows connectivity molecules best characterize these neuron groups.

Dopamine and GPCR-mediated modulation of DN1 clock neurons gates the circadian timing of sleep

The paper identifies dopamine and GPCR-mediated modulation in Drosophila clock neurons that regulate sleep timing.

A transcriptomic taxonomy of Drosophila circadian neurons around the clock

The paper characterizes Drosophila circadian neurons using single-cell RNA sequencing, identifying 17 cell categories with time-dependent gene expression patterns.

Bantam regulates the adult sleep circuit in Drosophila

This study identifies bantam as a regulator of sleep in Drosophila by inhibiting specific wake-promoting neurons during the night.