Author

Carlos A. Ramos‐Guzmán

University of BristolORCID 0000-0002-7701-377XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 1 Approach:biophysical modeling· 1 Approach:experimental assay· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Adrian John MulhollandiD· 2 shared Binqian Zou· 1 shared Chuanying Niu· 1 shared Gian Marco ElisiiD· 1 shared Giovanni BottegoniiD· 1 shared Haopeng Lin· 1 shared JAMES M. SPENCERiD· 1 shared Jiacheng GuiiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersBiochemistry

Adrian John MulhollandORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Redox Control of S-sulfocysteine Formation in Adenosine Phosphosulfate Reductase

Matilda Ymeraj, Carlos A. Ramos‐Guzmán, Marko Hanževački, Gian Marco Elisi, Giovanni Bottegoni, Adrian John Mulholland

This study investigates how the redox state of an iron-sulfur cluster in APSR from Pseudomonas aeruginosa influences catalytic activity and substrate binding through molecular simulations.

bioRxiv · Sep 8, 2026 · PreprintBiochemistry

Enhanced Target Binding by Leritrelvir Restores Dimerization of Mpro Mutants and Mitigates Drug Resistance

Xiaodong Huang, Petr Kuzmič, S Zhang, Carlos A. Ramos‐Guzmán, Xiaoxin Chen, Jiacheng Gui, Qi Li, Shujuan Yan, Binqian Zou, Chuanying Niu, Y ZHAO, Haopeng Lin, Nannan Wang, Jiaheng Chen, Xinwen Chen, , Xiaoli Xiong

This study evaluates leritrelvir's effectiveness against Mpro variants with resistance mutations, showing it restores dimerization and maintains inhibitory activity better than nirmatrelvir.

bioRxiv · Jun 10, 2026 · PreprintMolecular Biology