Author

Sourav Saha

National Institutes of HealthORCID 0000-0002-0854-5991Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Assay:ChIP-seq· 1 Assay:DNA methylation· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Liton Kumar SahaiD· 2 shared Yves G. PommieriD· 2 shared Anjali DhalliD· 1 shared Anthony K. L. LeungiD· 1 shared Beverly A. MockiD· 1 shared Hongliang ZhangiD· 1 shared Isabel R. UribeiD· 1 shared Ken Chih-Chien ChengiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersCancer Biology

Liton Kumar SahaORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintMar 13, 2025

Topoisomerase IIIb protects from tumorigenesis and immune dysregulation

Md Rasel Al Mahmud, Simone Andrea Baechler, Anjali Dhall…·Yves G. Pommier

This study shows that Top3b loss accelerates lymphoma development and causes immune dysregulation in mice through R-loop accumulation and immune signaling activation.

1 citation

mouseDNA methylation

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Molecular BiologyScience AdvancesPeer-reviewedJan 10, 2025

Flap endonuclease 1 repairs DNA-protein crosslinks via ADP-ribosylation

Yilun Sun, Lisa M. Miller Jenkins, Lara H. El Touny…·Yves G. Pommier

This study identifies FA-induced DNA-protein crosslinks (DPCs) and discovers that FEN1 repairs them via PARylation, revealing a novel PARP1-FEN1 pathway for DPC repair.

14 citations

humanexperimental assay

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