Anders Henrik Lund

Cytosolic and ER-associated ribosomes share rRNA 2'-O-methylation landscapes across human cell types

The paper compares 2'-O-methylation patterns of cytosolic and ER-associated ribosomes across human cell types and finds minimal compartment-specific differences.

Synthetic circRNAs employ IRES activity for translation in cells and in cell-free translation systems

The paper examines the translation efficiency of synthetic circRNAs using different IRESes in human cells and in vitro systems, finding that several IRESes effectively drive circRNA translation.

Ribosomal RNA 2'-O-methylation dynamics impact cell fate decisions

The paper examines how changes in rRNA 2'-O-methylation during development and differentiation affect cell fate decisions in mouse and human cells.

FUS modulates the level of ribosomal RNA modifications by regulating a subset of snoRNA expression

This study shows FUS regulates snoRNA expression, affecting rRNA modifications like 2-O-Me and pseudouridylation, which may contribute to ALS pathology.