Sebastian Herzog

This study identifies dual roles of ERH in primary miRNA biogenesis, showing it suppresses miRNA processing through DGCR8 binding and facilitates cluster assistance independently of this interaction.

The paper identifies TXNIP as a regulator of amino acid uptake during cellular quiescence by mediating endocytosis of the LAT1/SLC7A5 transporter.

The paper shows that caspase-2 triggers apoptosis in cells with extra centrosomes, preventing polyploidization through mitochondrial pathways.

The paper identifies SAFB2 as a co-factor enabling the processing of suboptimal miRNA stem-loop structures in clustered primary transcripts.