Author

Pablo Manfredi

University of BaselORCID 0000-0002-0900-1910Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

Urs JenaliD· 3 shared Adrian EgliiD· 1 shared Alexander KlotziD· 1 shared Alexander SchmidtiD· 1 shared Andrea RockeriD· 1 shared Andreas KaczmarczykiD· 1 shared Anna SintsovaiD· 1 shared Anne‐Florence BitboliD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersMicrobiology

Urs JenalORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

MicrobiologybioRxivPreprintJun 29, 2026

Competition against the intestinal microbiota selects for pathoadaptive traits in ESBL E. coli

Pramod Kumar Jangir, Leonardo F. Lemos Rocha, Marco Molari…·Médéric Diard

This study identifies how the intestinal microbiota drives the evolution of pathoadaptive traits in ESBL E. coli through adhesion and biofilm formation.

DOI 10.64898/2026.06.25.730905

mouseexperimental assay

𝕏 PostBluesky

MicrobiologybioRxivPreprintOct 24, 2025

Coenzyme A depletion causes antibiotic tolerance in Pseudomonas aeruginosa

Pablo Manfredi, Isabella Santi, Enea Maffei…·Urs Jenal

This study identifies coenzyme A depletion as a cause of antibiotic tolerance in Pseudomonas aeruginosa using proteomic, metabolomic, and machine learning analyses.

3 citations

bacteria (other)proteomics

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MicrobiologybioRxivPreprintAug 12, 2025

Genome-wide high-density CRISPR interference screens reveal condition-specific metabolic vulnerabilities in Pseudomonas aeruginosa PAO1

Andreas Kaczmarczyk, Alexander Klotz, Pablo Manfredi, Urs Jenal

The paper uses CRISPRi screens to identify metabolic vulnerabilities in P. aeruginosa PAO1 under different conditions, revealing key genes for targeting chronic infections.

2 citations

bacteria (other)genetic perturbation / CRISPR

𝕏 PostBluesky