Michelle R. Lacey

The paper shows that promoter-adjacent DNA hypermethylation in TBX15 reduces gene expression in myoblasts and skeletal muscle without silencing it, suggesting a regulatory role in preventing overexpression.

The paper examines the epigenetic regulation and expression of five fibrosis-related genes in cardiac fibrosis, identifying super-enhancers and enhancer chromatin features associated with their expression.

The paper evaluates epigenetic methods using reference materials, finding high concordance between assays and differences in performance across platforms.

The paper examines the epigenetic features and expression patterns of 21 skeletal muscle-associated genes from four families, identifying tissue-specific regulatory elements and potential regulatory lncRNAs.

The paper examines DNA hypermethylation in developmental contexts, identifying gene-specific methylation patterns and their links to transcriptional regulation in human cell types.