Yuichi Iino

The paper introduces image-scanning light-sheet microscopy to enable high-speed volumetric imaging of complex biological dynamics with improved speed while maintaining resolution and efficiency.

WormTracer improves posture analysis of C. elegans by analyzing sequences of images concurrently, generating more accurate eigenworms for posture representation.

The paper presents a new gap-free, telomere-to-telomere reference genome for C. elegans, CGC1, improving upon previous assemblies and providing a more complete genome.

This study identifies JNK and p38 MAPK pathways in C. elegans that mediate salt chemotaxis learning, with distinct roles in avoiding low and high salt concentrations.

This paper shows that C. elegans chemosensory neuron ASEL mediates opposing learned chemotactic responses to glucose and salt, regulated by kinase-phosphatase signaling.

The paper analyzes whole-brain imaging data of C. elegans to decompose neural dynamics and model information flow using time-delay embedding, independent component analysis, and dimensionality reduction techniques.

This study identifies cell-specific insulin/IGF signaling mechanisms in C. elegans that regulate presynaptic glutamate release during aversive olfactory learning.

This study identifies CLH-1, a ClC chloride channel, as essential for salt chemotaxis in C. elegans by regulating chloride and calcium dynamics in the ASER neuron.

The paper creates a dataset of neuron expression patterns and positions in C. elegans to improve annotation of whole-brain imaging data.

This study develops an ensemble learning approach for automated annotation of whole-brain C. elegans imaging data, achieving 25% error in neuron annotation.