Cornelia I. Bargmann

SynaptoTagMe enables in vivo mapping and modulation of neurotransmission at single-cell resolution in C. elegans by fluorescently labeling and ablating vesicular transporters.

The paper identifies E. coli metabolic mutants that affect C. elegans foraging behavior and shows how serotonin and dopamine signaling modulates responses to different diets.

The paper compares mating behaviors between female and hermaphrodite nematodes, finding differences in chemotaxis and receptivity linked to the ODR-7 transcription factor and sperm presence.

This study shows that sensory neurons in C. elegans integrate internal and external cues to couple arousal states with foraging decisions.

This paper introduces an optogenetic voltage-clamp technique for precise control of cellular voltage in live animals, demonstrating its application in C. elegans and rat neurons.

This study identifies cell-specific insulin/IGF signaling mechanisms in C. elegans that regulate presynaptic glutamate release during aversive olfactory learning.

The paper identifies neuromodulatory circuits in C. elegans that control sickness behavior dynamics during infection by Pseudomonas aeruginosa.

The paper shows how RIM interneurons in C. elegans use depolarized and hyperpolarized states to regulate motor behavior transitions through neurotransmitters and gap junctions.

The paper shows that AIA interneurons in C. elegans use AND-gate logic to integrate sensory inputs for reliable responses to attractive odors.

The paper identifies parallel multimodal circuits in C. elegans that control local search behavior after food removal, showing redundancy and integration of chemosensory and mechanosensory inputs.

This study identifies a GPCR, str-217, in C. elegans that mediates DEET resistance by altering chemotaxis behavior through increased pause length.

The paper discovers that C. elegans AWA olfactory neurons fire all-or-none action potentials, suggesting digital coding in addition to analog coding.

The paper compares synaptic dynamics between two C. elegans glutamatergic neurons, showing distinct exocytosis and retrieval properties linked to tonic and phasic release modes.