Author

Edgar González-Buendía

Howard Hughes Medical InstituteORCID 0000-0002-0938-0869Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Organism:human· 1

Frequent Co-Authors

Danny ReinbergiD· 2 shared Havva OrtabozkoyuniD· 2 shared Aristotelis TsirigosiD· 1 shared Esteban O. MazzoniiD· 1 shared Hyunwoo ChoiD· 1 shared Pin‐Yao HuangiD· 1 shared Sang Yong KimiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

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2 shared papersBiochemistry

Danny ReinbergORCID

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2 papers

Recent·Most cited

BiochemistryScience AdvancesPeer-reviewedOct 30, 2026

PDS5A and TOP2B cooperate for chromatin recruitment via CTCF

Edgar González-Buendía, Havva Ortabozkoyun, Danny Reinberg

This study identifies a functional interaction between PDS5A and TOP2B at CTCF-bound chromatin sites, showing their cooperative recruitment and impact on gene expression and chromatin structure in gliomas.

DOI 10.1126/sciadv.aeg2830

humanDNA methylation

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GeneticsMolecular CellPeer-reviewedAug 23, 2024

Members of an array of zinc finger proteins specify distinct Hox chromatin boundaries

Havva Ortabozkoyun, Pin‐Yao Huang, Edgar González-Buendía…·Danny Reinberg

The paper identifies zinc finger proteins that establish distinct chromatin boundaries at Hox clusters during development, working with cohesin to regulate cell fate.

27 citations

mouseChIP-seq

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