Knockout of the longevity gene Klotho perturbs aging- and Alzheimer's disease-linked brain microRNAs and tRNA fragments
Serafima Dubnov, Estelle R. Bennett, Nadav Yayon, Or Yakov, David Alan Bennett, Sudha S. Seshadri, Elliott Jay Mufson, Yonat Tzur, David Greenberg, Makoto Kuro‐o, Iddo Paldor, Carmela R. Abraham, Hermona Soreq
This study shows that Klotho knockout affects brain microRNAs and tRNA fragments linked to aging and Alzheimer's disease in both mice and humans.
Communications Biology · Jun 11, 2024Peer-reviewedNeuroscience