Per Sunnerhagen

The paper shows that ribosomes modulate transcriptome abundance through frameshifts and out-of-frame mRNA decay in yeast under poor nutritional conditions, with conservation across species.

The paper develops a yeast-based platform to identify Plasmodium vivax DHS inhibitors, finding two compounds that selectively inhibit parasite DHS over human DHS.

This study adapts SLAM-Seq to measure mRNA half-lives in yeast, identifies NMD targets, and finds 230 novel transcripts regulated by NMD.

The paper describes a genetic trap in yeast for identifying small molecule inhibitors of SARS-CoV-2 main protease, demonstrating its effectiveness with an established inhibitor.

This study introduces a high-throughput experimental framework to screen genetic factors affecting conjugation-based antibiotic resistance transmission in E. coli.